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Continue to Iris Biotech GmbHSend request to US distributorChemischer Name: 3-(1-trityl-1H-imidazol-4-yl)propan-1-amine
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This compound has been found as fragment in a new class of potent and selective agonists histamine H2 and H4 receptor ligands (H2R, H4R), and inhibitors of histamine N-methyltransferases.
Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists; N. Kagermeier, K. Werner, M. Keller, P. Baumeister, G. Bernhardt, R. Seifert and A. Buschauer; Bioorg Med Chem 2015; 23: 3957-69. https://doi.org/10.1016/j.bmc.2015.01.012
Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H4 receptor agonists; P. Igel, R. Geyer, A. Strasser, S. Dove, R. Seifert and A. Buschauer; Journal of medicinal chemistry 2009; 52: 6297-313. https://doi.org/10.1021/jm900526h
Imidazole derivatives as a novel class of hybrid compounds with inhibitory histamine N-methyltransferase potencies and histamine hH3 receptor affinities; S. Graßmann, J. Apelt, W. Sippl, X. Ligneau, H. H. Pertz, Y. H. Zhao, J.-M. Arrang, C. R. Ganellin, J.-C. Schwartz, W. Schunack and H. Stark; Bioorganic & Medicinal Chemistry 2003; 11: 2163-2174. https://doi.org/10.1016/s0968-0896(03)00120-2
[3-(1H-imidazol-4-yl)propyl]guanidines containing furoxan moieties: a new class of H3-antagonists endowed with NO-donor properties; M. Bertinaria, A. D. Stilo, P. Tosco, G. Sorba, E. Poli, C. Pozzoli, G. Coruzzi, R. Fruttero and A. Gasco; Bioorg Med Chem 2003; 11: 1197-205. https://doi.org/10.1016/s0968-0896(02)00651-x
Discovery of a Novel Non-Peptide Somatostatin Agonist with SST4Selectivity; M. Ankersen, M. Crider, S. Liu, B. Ho, H. S. Andersen and C. Stidsen; Journal of the American Chemical Society 1998; 120: 1368-1373. https://doi.org/10.1021/ja973325x
Novel H3 receptor antagonists. Sulfonamide homologs of histamine; R. Wolin, M. Connolly, A. Afonso, J. A. Hey, H. She, M. A. Rivelli, S. M. Willams and R. E. West, Jr.; Bioorg Med Chem Lett 1998; 8: 2157-62. https://doi.org/10.1016/s0960-894x(98)00379-5
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