Further Information
The Clt (2-chlorotrityl) protecting group is more stable than the commonly used Trt group and is being deprotected with 95%TFA in dichloromethane. The main application is in peptide synthesis, whenever certain treatments and modifications of the peptide are being applied, where the standard His(Trt) protection is too labile. References: Aletras A., Barlos K. et al; Int. J. Pept. Protein Res. 1995; 45(5): 488-496. Barlos K. et al; Int. J. Pept. Protein Res. 1991; 38(6): 555-561. Sarah L.M. et al, in „Fmoc Solid Phase Synthesis. A practical approach“, Ed.: Chan W.C., White P.D. Oxford University Press 2000, page 177.
Details
The Clt (2-chlorotrityl) protecting group is more stable than the commonly used Trt group and is being deprotected with 95%TFA in dichloromethane. The main application is in peptide synthesis, whenever certain treatments and modifications of the peptide are being applied, where the standard His(Trt) protection is too labile. References: Aletras A., Barlos K. et al; Int. J. Pept. Protein Res. 1995; 45(5): 488-496. Barlos K. et al; Int. J. Pept. Protein Res. 1991; 38(6): 555-561. Sarah L.M. et al, in „Fmoc Solid Phase Synthesis. A practical approach“, Ed.: Chan W.C., White P.D. Oxford University Press 2000, page 177.
Additional Information
| ART-NO | FAA1060 |
|---|---|
| DETAIL NAME | N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-im-2-chlorotrityl-L-histidine |
| FORMULA | C40H32ClN3O4 |
| MOLECULAR WEIGHT | 654,16 |
| Bezeichnung Mol Ge | g/mole |
| QUANTITY | 5 g |
| neu | N |
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