Further Information
Fluorogenic substrate for alpha-D-mannosidase yielding a blue fluorescent solution upon cleavage. Used for determination of lectin in very dilute solution by fluorescence quenching, in studies of the kinetics of saccharide binding to the dimer form of concanavalin A. Further used for diagnosis of alpha-mannosidosis by measuring alpha-mannosidase in plasma. 1. Clegg R.M., Loontiens F.G., Jovin T.M., Binding of 4-methylumbelliferyl alpha-D-mannopyranoside to dimeric concanavalin A: fluorescence temperature-jump relaxation study. Biochemistry 1977, 16, 167-75. 2. Datta P.K., Bera S.C., Determination of lectin in very dilute solution with umbelliferyl sugars by fluorescence quenching. Anal. Chim. Acta 1989, 220, 225. 3. Prence E.M., Natowicz M.R., Diagnosis of alpha-mannosidosis by measuring alpha-mannosidase in plasma. Clin. Chem. 1992, 38, 501-3. 4. Yoshihisa T., Ohsumi Y., Anraku Y., Solubilization and purification of alpha-mannosidase , a marker enzyme of vacuolar membranes in Saccharomyces cerevisiae. J. Biol. Chem. 1988, 263, 5158-63.
Details
Fluorogenic substrate for alpha-D-mannosidase yielding a blue fluorescent solution upon cleavage. Used for determination of lectin in very dilute solution by fluorescence quenching, in studies of the kinetics of saccharide binding to the dimer form of concanavalin A. Further used for diagnosis of alpha-mannosidosis by measuring alpha-mannosidase in plasma. 1. Clegg R.M., Loontiens F.G., Jovin T.M., Binding of 4-methylumbelliferyl alpha-D-mannopyranoside to dimeric concanavalin A: fluorescence temperature-jump relaxation study. Biochemistry 1977, 16, 167-75. 2. Datta P.K., Bera S.C., Determination of lectin in very dilute solution with umbelliferyl sugars by fluorescence quenching. Anal. Chim. Acta 1989, 220, 225. 3. Prence E.M., Natowicz M.R., Diagnosis of alpha-mannosidosis by measuring alpha-mannosidase in plasma. Clin. Chem. 1992, 38, 501-3. 4. Yoshihisa T., Ohsumi Y., Anraku Y., Solubilization and purification of alpha-mannosidase , a marker enzyme of vacuolar membranes in Saccharomyces cerevisiae. J. Biol. Chem. 1988, 263, 5158-63.
Additional Information
| ART-NO | GBB1277 |
|---|---|
| CAS-NO | 28541-83-5 |
| DETAIL NAME | 4-Methylumbelliferyl-alpha-D-mannopyranoside, 98% |
| FORMULA | C16H18O8 |
| MOLECULAR WEIGHT | 338,32 |
| Bezeichnung Mol Ge | g/mole |
| QUANTITY | 250 mg |
| neu | N |
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