Further Information
Alpha-helical peptide antibiotic produced by the fungus Trichoderma viride. It forms tetra- and hexameric voltage gated ion channels in membranes and can mimic nerve action potential across artificial membrandes. 1. Fox, R.O. Jr, Richards, F.M., A voltage-gated ion channel model inferred from the crystal structure of alamethicin at 1.5-A resolution. Nature. 1982; 300(5890):325-30. 2. Mathew, M.K., Balaram P., Alamethicin and related membrane channel forming polypeptides. Mol Cell Biochem. 1983; 50(1):47-64. 3. Stella, L., et al., Alamethicin interaction with lipid membranes: a spectroscopic study on synthetic analogues. Chem Biodivers. 2007; 4(6):1299-312.
Details
Alpha-helical peptide antibiotic produced by the fungus Trichoderma viride. It forms tetra- and hexameric voltage gated ion channels in membranes and can mimic nerve action potential across artificial membrandes. 1. Fox, R.O. Jr, Richards, F.M., A voltage-gated ion channel model inferred from the crystal structure of alamethicin at 1.5-A resolution. Nature. 1982; 300(5890):325-30. 2. Mathew, M.K., Balaram P., Alamethicin and related membrane channel forming polypeptides. Mol Cell Biochem. 1983; 50(1):47-64. 3. Stella, L., et al., Alamethicin interaction with lipid membranes: a spectroscopic study on synthetic analogues. Chem Biodivers. 2007; 4(6):1299-312.
Additional Information
| ART-NO | LS-1075 |
|---|---|
| CAS-NO | 27061-78-5 |
| DETAIL NAME | Almethicin, Antibiotic U-22324; Ac-Aib-Pro-Aib-Ala-Aib-Ala-Gln-Aib-Val-Aib-Gly-Leu-Aib-Pro-Val-Aib-Aib-Glu-Gln-Phenylalaninol |
| FORMULA | C92H150N22O25 |
| MOLECULAR WEIGHT | 1964,3 |
| Bezeichnung Mol Ge | g/mole |
| QUANTITY | 0 |
| neu | N |
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