Further Information
Antibiotic produced by Streptomyces griseolus. Protein synthesis inhibitor: blocks peptidyl transferase acticity of 60S ribosomal subunit. Induces apoptosis in a variety of cells. For example jurkat cells, ventricular myocytes, promyelocytic leukemia cells and colon adenocarcinoma cells. Potential psychiatric drug that may inhibit long term memories. 1. Grollman, A.P., Inhibitors of protein biosynthesis. II. Mode of action of anisomycin. J Biol Chem. 1967; 242(13):3226-33. 2. Barrientos, R.M. et al., Memory for context is impaired by injecting anisomycin into dorsal hippocampus following context exploration. Behav Brain Res. 2002; 134(1-2):299-306.
Details
Antibiotic produced by Streptomyces griseolus. Protein synthesis inhibitor: blocks peptidyl transferase acticity of 60S ribosomal subunit. Induces apoptosis in a variety of cells. For example jurkat cells, ventricular myocytes, promyelocytic leukemia cells and colon adenocarcinoma cells. Potential psychiatric drug that may inhibit long term memories. 1. Grollman, A.P., Inhibitors of protein biosynthesis. II. Mode of action of anisomycin. J Biol Chem. 1967; 242(13):3226-33. 2. Barrientos, R.M. et al., Memory for context is impaired by injecting anisomycin into dorsal hippocampus following context exploration. Behav Brain Res. 2002; 134(1-2):299-306.
Additional Information
| ART-NO | LS-1010 |
|---|---|
| CAS-NO | 22862-76-6 |
| DETAIL NAME | Anisomycin |
| FORMULA | C14H19NO4 |
| MOLECULAR WEIGHT | 265,31 |
| Bezeichnung Mol Ge | g/mole |
| QUANTITY | 250 mg |
| neu | N |
| synonyms | Flagecidin, 2-[(4-methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetat, (2R,3S,4S)-2-(4-methoxybenzyl)-3,4-pyrrolidinediol-3-acetate |
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