Further Information
Tetracyclic diterpene antibiotic with antiviral, antineoplastic and antimitotic properties. It is a reversible inhibitor of eukaryotic nuclear DNA replication and blocks the cell cycle at early S phase. Furthermore it is known as a specific inhibitor of DNA polymerase A,D in eukaryotic cells and in some viruses. Aphidicolin belongs to the group of mycotoxins. Origin: Nigrospora oryzae. Spadari, S. et al. Control of cell division by aphidicolin without adverse effects upon resting cells. Arzneimittelforschung. 1985; 35(7):1108-16.
Details
Tetracyclic diterpene antibiotic with antiviral, antineoplastic and antimitotic properties. It is a reversible inhibitor of eukaryotic nuclear DNA replication and blocks the cell cycle at early S phase. Furthermore it is known as a specific inhibitor of DNA polymerase A,D in eukaryotic cells and in some viruses. Aphidicolin belongs to the group of mycotoxins. Origin: Nigrospora oryzae. Spadari, S. et al. Control of cell division by aphidicolin without adverse effects upon resting cells. Arzneimittelforschung. 1985; 35(7):1108-16.
Additional Information
| ART-NO | LS-1011 |
|---|---|
| CAS-NO | 38966-21-1 |
| DETAIL NAME | (+)-Aphidicolin |
| FORMULA | C20H34O4 |
| MOLECULAR WEIGHT | 338,49 |
| Bezeichnung Mol Ge | g/mole |
| QUANTITY | 0 |
| neu | N |
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