Alkyne-myristic acid

Chemischer Name: 13-Tetradecynoic acid // Synonyme: Tetradec-13-ynoic acid

  • Art-Nr.:RL-2055
  • CAS Nr.:82909-47-5
  • Formel:C14H24O2
  • Molare Masse:224,34 g/mol

Startet von 400,00 €

Gruppiert Produkte - Artikel
Anzahl Verpackungsgröße Preis SKU
100 mg
400,00 €
RL-2055.0100
250 mg
800,00 €
RL-2055.0250
1 g
2.400,00 €
RL-2055.1000
Sicherheitsdatenblätter
description

Linker for bioconjugation via Click reaction. Protein acylation with this compound leads to rapid, selective and robust fluorescent detection with chemical reporters.

references

Robust fluorescent detection of protein fatty-acylation with chemical reporters; G. Charron, M. M. Zhang, J. S. Yount, J. Wilson, A. S. Raghavan, E. Shamir and H. C. Hang; J Am Chem Soc 2009; 131: 4967-75. https://doi.org/10.1021/ja810122f


Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry; M. C. Yap, M. A. Kostiuk, D. D. Martin, M. A. Perinpanayagam, P. G. Hak, A. Siddam, J. R. Majjigapu, G. Rajaiah, B. O. Keller, J. A. Prescher, P. Wu, C. R. Bertozzi, J. R. Falck and L. G. Berthiaume; J Lipid Res 2010; 51: 1566-80. https://doi.org/10.1194/jlr.D002790


SIRT6 regulates TNF-alpha secretion through hydrolysis of long-chain fatty acyl lysine; H. Jiang, S. Khan, Y. Wang, G. Charron, B. He, C. Sebastian, J. Du, R. Kim, E. Ge, R. Mostoslavsky, H. C. Hang, Q. Hao and H. Lin; Nature 2013; 496: 110-3. https://doi.org/10.1038/nature12038


The biology and enzymology of protein N-myristoylation; T. A. Farazi, G. Waksman and J. I. Gordon; J Biol Chem 2001; 276: 39501-4. https://doi.org/10.1074/jbc.R100042200


The growing impact of click chemistry on drug discovery; H. C. Kolb and K. B. Sharpless; Drug Discov Today 2003; 8: 1128-37. https://doi.org/10.1016/S1359-6446(03)02933-7


Efficient construction of therapeutics, bioconjugates, biomaterials and bioactive surfaces using azide-alkyne "click" chemistry; J. F. Lutz and Z. Zarafshani; Adv Drug Deliv Rev 2008; 60: 958-70. https://doi.org/10.1016/j.addr.2008.02.004


Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives; A. Vila, K. A. Tallman, A. T. Jacobs, D. C. Liebler, N. A. Porter and L. J. Marnett; Chemical research in toxicology 2008; 21: 432-44. https://doi.org/10.1021/tx700347w


Chemical Reporters of Protein Acylation; H. C. N. Y. Hang, NY, US), Charron, Guillaume (NEW YORK, NY, US), Wilson, John P. (NEW YORK, NY, US), Raghavan, Anuradha (NEW HAVEN, CT, US), Zhang, Mingzi (NEW YORK, NY, US), Yang, Yu-ying (STAMFORD, CT, US), Rangan, Kavita (NEW YORK, NY, US), Tsou, Lun K. (NEW YORK, NY, US), Yount, Jacob (BROOKLYN, NY, US); 2010.


Chemical reporters for exploring protein acylation; E. Thinon and H. C. Hang; Biochem Soc Trans 2015; 43: 253-61. https://doi.org/10.1042/BST20150004

Bulk oder Großmengen-Bestellung?

Sie benötigen größere Mengen für Ihre Entwicklung oder Produktion?

Benötigen Sie weitere Informationen über dieses Produkt?

kontaktieren Sie uns

Schneller Kontakt

Bitte senden Sie mir mehr Informationen über

Produkte, die Sie auch interessieren könnten!