Life Sciences

  1. A Tetrazole-Substituted Lysine as PTM Isostere

    The tetrazole isostere of malonyllysine is thermally stable and does not suffer from decarboxylation. Discover our building blocks suitable for incorporation via solid-phase peptide synthesis.

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  2. Cyanobenzothiazole (CBT) Derivatives for “Click” Conjugation

    Discover the cyanobenzothiazole (CBT) click reaction, a not (yet) so well-known biocompatible and bio-orthogonal mechanism faster than the famous azide-alkyne cycloaddition (CuAAC).

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  3. Carbamidomethylated Cysteine as SPPS Building Block

    Our building block Fmoc-L-Cys(Cam)-OH enables peptides resembling reduced and carbamido-methylated protein fragments by standard SPPS without error-prone modification reactions.

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  4. PotM: Plant-Derived Cholesterol for LNP Drug Delivery

    Plant-derived Cholesterol of high and consistent product quality in accordance with Pharmacopoeia requirements to replace established animal source material in LNP formulation. Read on!

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  5. Fluorogenic Protease Substrates with Enhanced Signal-to-Noise-Ratio

    Shine bright like our fluorophores! Learn how our superior fluorogenic protease substrate peptides can enhance your test performance. Click here to gather more information and discover available products!

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  6. PotM: Perfluorobiphenyl Building Blocks for Site-Selective Cysteine Conjugation

    Herein, we present functionalized perfluorobiphenyl building blocks which can be used for site-selective π-clamp mediated cysteine conjugation. Read on for more details about this general method!

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  7. PotM: Argpyrimidine Building Block for SPPS

    Argpyrimidine is the result of a Maillard Reaction-like nonenzymatic posttranslational modification. You want to investigate the effect of this change on function and stability? Get the building block!

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  8. Choose your Taste – Functionalized Halo/Snap/Clip Substrates

    The HaloTag®, SNAP-Tag® and CLIP-TagTM represent versatile tools for the specific, covalent attachment of in principle any molecule of choice to a protein of interest. Discover our substrates!

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  9. PotM: His Tags for the Chemical Modification of Peptides

    Jensen et al. developed two methods that use poly-His sequences to direct the highly selective acylation of proteins, either at the N-terminus or at a specific Lys residue. Read on for more information.

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  10. DTT and Spermidine for RNA Buffers and Vaccine Production

    See how our “mRNA grade” DTT and Spermidine can support also your nucleic acid production. Read on for more information.

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