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Boc-L-Ser[Psi(Me,Me)Pro]-OH
Chemischer Name: (S)-3-(tert-butoxycarbonyl)-2,2-dimethyloxazolidine-4-carboxylic acid // Synonyme: Boc-Ser[Psi(Me,Me)Pro]-OH
- Art-Nr.:PSI1630
- CAS Nr.:139009-66-8
- Formel:C11H19NO5
- Molare Masse:245,28 g/mol
- Reinheit:min. 99%
- Enantiomerenreinheit:min. 99,7%
Startet von 70,00 €
description
Serine-derived Pseudoproline monomer for SPPS. This building-block can be successfully coupled with many amino-acids using modern coupling techniques avoiding the need for pseudoproline dipeptides and giving the possibility to introduce pseudoprolines in peptides containing non-natural or rare amino-acids. See also the Fmoc-derivative FAA8590.
references
Reference:
Scope and limitations of pseudoprolines as individual amino acids in peptide synthesis; D. A. Senko, N. D. Timofeev, I. E. Kasheverov, I. A. Ivanov; Amino Acids 2021; 53: 665-671. https://doi.org/10.1007/s00726-021-02973-1.
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Related news
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News Amino Acids Building BlocksAcylation Efficiencies on Ser and Thr Pseudoproline Monomers
In two joint studies together with Prof. F. Albericio we investigated the coupling efficiencies of Ser and Thr pseudoproline monomers and their use
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