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Chemical name: N-alpha-t-Butyloxycarbonyl-beta,beta-dimethyl-proline (rac.) // Synonyms: Boc-beta,beta-diMe-Pro-OH (rac.), (R,S)-Boc-3,3-dimethyl-proline, (R,S)-Boc-3,3-dimethyl-pyrrolidine-2-carboxylic acid, 1-(tert-butoxycarbonyl)-3,3-dimethylpyrrolidine-2-carboxylic acid
|Molecular weight:||243,30 g/mol|
beta,beta-Dimethylation of amino acids stabilizes appropriate peptides towards digestion by proteases.
Benzyl 2-Cyano-3,3-Dimethyl-1-pyrrolidinecarboxylate, a Versatile Intermediate for the Synthesis of 3,3-Dimethylproline Derivatives; Jesus R. Medina, Charles W. Blackledge, Karl F. Erhard, Jeffrey M. Axten, and William H. Miller; J. Org. Chem. 2008; 73: 3946-3949. DOI: 10.1021/jo7027163.
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