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Chemical name: N-alpha-(t-butyloxycarbonyl)-L-(4-bromo)-homoalanine tert-butyl ester // Synonyms: N-alpha-(t-butyloxycarbonyl)-L-(4-bromo)-homoalanine t-butyl ester, Boc-L-(4-bromo)-homoalanine tert-butyl ester, Boc-L-(4-bromo)-homoalanine t-butyl ester, 1,1-Dimethylethyl(2S)-4-bromo-2-[[(1,1-di methylethoxy)carbonyl]amino]butanoate, Tert-butyl
Starting at $91.00
This brominated azidohomoalanine building block is reported as precursor for the synthesis of hydrocarbon-bridged diaminodiacids, as functionalized linker, as well as for nucleobase peptide synthesis.
Discovery of Nucleic Acid Binding Molecules from Combinatorial Biohybrid Nucleobase Peptide Libraries; S. Pomplun, Z. P. Gates, G. Zhang, A. J. Quartararo, B. L. Pentelute; J. Am. Chem. Soc. 2020; 142(46): 19642-19651. https://doi.org/10.1021/jacs.0c08964.
Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state; M. J. van Haren, R. Taig, J. Kuppens, J. S. Toraño, E. E. Moret, R. B. Parsons, D. Sartini, M. Emanuelli, N. I. Martin; Org. Biomol. Chem. 2017; 15: 6656-6657. https://doi.org/10.1039/c7ob01357d.
Efficient synthesis of hydrocarbon-bridged diaminodiacids through nickel-catalyzed reductive cross-coupling; T. Wang, Y.-F. Kong, Y. Xu, J. Fan, H.-J. Xu, D. Bierer, J. Wang, J. Shi, Y.-M. Li; Tetrahedron Lett. 2017; https://doi.org/10.1016/j.tetlet.2017.09.006.
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