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Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
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Continue to Iris Biotech GmbHSend request to US distributorChemical name: Boc-2-oxohistidine // Synonyms: (S)-2-((tert-butoxycarbonyl)amino)-3-(2-oxo-2,3-dihydro-1H-imidazol-4-yl)propanoic acid, Boc-2-Oxo-Histidine, Boc-Oxohistidine, Boc-2-Oxo-L-Histidine, Boc-2-Oxohistidine,Boc-His(2-Oxo)-OH
Starting at $1,040.00
Histidine is one of the major oxidation targets due to its metal‐chelating property and susceptibility to metal‐catalyzed oxidation. The major product of histidine oxidation, 2-oxohistidine, has been identified as a stable marker of oxidative damage in biological system, associated with aging and neurodegenerative disorders. Peptide probes and peptide antigens containing 2‐oxohistidine will help to advance the study of non‐enzymatic posttranslational modification.
Synthesis of peptides containing 2‐oxohistidine residues and their characterization by liquid chromatography‐tandem mass spectrometry; C.‐F. Huang, Y.‐H. Liu, H.‐C. Tai; J. Pept. Sci. 2015; 21: 114-119. https://doi.org/10.1002/psc.2735.
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Oxidation is not only a known degradation pathway of proteins and peptides in vivo but is also a major side reaction for certain amino aci
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