Boc-L-His(2-Oxo)-OH

Chemical name: Boc-2-oxohistidine // Synonyms: (S)-2-((tert-butoxycarbonyl)amino)-3-(2-oxo-2,3-dihydro-1H-imidazol-4-yl)propanoic acid, Boc-2-Oxo-Histidine, Boc-Oxohistidine, Boc-2-Oxo-L-Histidine, Boc-2-Oxohistidine,Boc-His(2-Oxo)-OH

  • Product code:BAA4850
  • CAS No.:2580114-21-0
  • Formula:C11H17N3O5
  • Molecular weight:271.27 g/mol

Starting at $1,040.00

Grouped product items
Qty Packing unit Price SKU
100 mg
$1,040.00
BAA4850.0100
250 mg
$2,080.00
BAA4850.0250
description

Histidine is one of the major oxidation targets due to its metal‐chelating property and susceptibility to metal‐catalyzed oxidation. The major product of histidine oxidation, 2-oxohistidine, has been identified as a stable marker of oxidative damage in biological system, associated with aging and neurodegenerative disorders. Peptide probes and peptide antigens containing 2‐oxohistidine will help to advance the study of non‐enzymatic posttranslational modification.


references

Synthesis of peptides containing 2‐oxohistidine residues and their characterization by liquid chromatography‐tandem mass spectrometry; C.‐F. Huang, Y.‐H. Liu, H.‐C. Tai; J. Pept. Sci. 2015; 21: 114-119. https://doi.org/10.1002/psc.2735.

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