About us

History

On July 24th 1788, the Chemical Factory Marktredwitz (CFM) was founded as the first chemical factory in Germany. Around 100 years later, the Tropitzsch brothers acquired the company from the founder’s successors and intensified their research and development activities in the field of pesticides and other basic chemicals. Today, another 100 years later, the portfolio ranges from reagents for analytics, biotechnology, to specialties and intermediates for the pharmaceutical industry. In 2001, Iris Biotech GmbH was established as an offspring to further strengthen the market position in the areas of peptide synthesis and life sciences.

Mission

Having a holistic view of the world of peptides, Iris Biotech GmbH is today the number one address for any unusual compound required for the modification of peptides. Our mission as qualified supplier is to support our customers in their ongoing projects from research scale to commercial production by providing the most novel substances and latest technologies together with the required analytics and documentation.

Portfolio

Iris Biotech GmbH is a renowned, globally active company for innovation and know-how in the field of pharmaceuticals and biotechnology. Starting in 2001 with a small range of commodities for peptides, we meanwhile developed our portfolio to a unique list of standard reagents and unusual building blocks for various life science applications. With our custom synthesis service and our products in drug discovery, drug delivery, and diagnostics being available in laboratory quantities for the research sector up to multi ton scales distinguishes Iris Biotech GmbH as a globally and locally valued partner.

Drug Discovery:
Nearly endless variations are possible to equip a peptide with higher or lower rigidity, solubility, protease sensitivity, affinity, or efficacy. We offer protected amino acids, coupling reagents, linkers und resins, natural and unusual amino acids and their derivatives, fatty acid derivatives, as well as thousands of other building blocks to adapt existing sequences to individual needs. Moreover, with our custom synthesis capabilities we can pick up any idea of clients’ requirements.

Drug Delivery:
PEG polymers were pioneering a new drug delivery approach. Iris Biotech GmbH provides the world’s largest portfolio on PEGylation reagents ranging from short, monodisperse hydrophilic linkers, which can be used to increase solubility, to very long, polydisperse derivatives, which improve the pharmacokinetic properties of peptides, proteins and other biopharmaceuticals. All products are also available in multi-KG quantities and appropriate to cGMP. Next to those pioneer products, Iris Biotech GmbH presents novel polymers with improved biodegradability, rendering the advantages of polymer therapeutics transferable to small drug molecules thus opening the door to new treatment approaches such as combination therapy, personalized medicine or antibody-drug conjugates (ADC). As part of our new Linkerology section we provide various functionalized linkers – depending on the desired application either with a predetermined breaking point or defined stability, e.g. for solid phase peptide synthesis or as an ADC linker. Newly added to our portfolio are fullerenes, showing distinct photo-/electrochemical and physical properties thus being useful tools for various fields of research, e.g. as antioxidant, as radical scavenger, for filling hydrophobic binding pockets, or as carrier in drug delivery.

Diagnostics & Analytics:
Our latest field of activities for life sciences including inhibitors, metabolites, substrates and fluorescent dyes. Furthermore, we offer natural products with biological and pharmaceutical activity like immunosuppressants (aflatoxins, cyclosporins, geldanamycin, rapamycin, etc.) or carbohydrates (xylan, as well as derivatives of arabinose, galactose, glucose, etc.), enzyme substrates, and special proteins, diagnostics, and biochemistry tools. The latest addition to this field are Amadori and Maillard reaction products, which play an important role in the food industry as quality indicators as well as in the pharmaceutical sector as biomarker, e.g. for aging and diabetes.