Fmoc-D-Lys(Mtt)-OH

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-4-methyltrityl-D-lysine // Synonyms: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-(4-methlphenyl)diphenylmethyl-D-lysine

  • Product code:FAA1130
  • CAS No.:198544-94-4
  • Formula:C41H40N2O4
  • Molecular weight:624.78 g/mol

Starting at $221.00

Grouped product items
Qty Packing unit Price SKU
5 g
$221.00
FAA1130.0005
25 g
$871.00
FAA1130.0025
Safety Data Sheets
description

Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation.


references

A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy, Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. BennyGerber, and Assaf Friedler; Angew. Chem. Int. Ed. 2014; 53: 9450-9455. DOI: 10.1002/anie.201402789.

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