Fmoc-L-F2Pmp-OH

Chemical name: 4-(Difluorophosphonomethyl)-N-alpha-(9-Fluorenylmethyloxycarbonyl) -L-Phenylalanine // Synonyms: Fmoc-L-Phe(4-CF2PO3)-OH, Fmoc-L-p-(Phosphono-difluoromethyl)phenylalanine, (2S)-3-[4-[Difluoro(phosphono)methyl]phenyl]-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)propanoic acid, 4-(Difluorophosphonomethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-Phenylalanine

Art-No. :FAA5595
CAS-No. :160751-44-0
Formula :C25H22F2NO7P
Molecular weight :517.42 g/mol
Grouped product items
Qty Weight Price SKU
100 mg
$810.00
FAA5595.0100
250 mg
$1,620.00
FAA5595.0250
1 g
$4,860.00
FAA5595.0001
description
Hydrolysis-stable mimic of Phosphotyrosine; fluorination makes the phoshonic acid more acidic and thus a better mimic of phosphotyrosine than Pmp (compare to FAA1745 Fmoc-L-Pmp-OH and FAA5590 Fmoc-L-Pmp(OtBu)2-OH)

references
Phosphatase-Stable Phosphoamino Acid Mimetics That Enhance Binding Affinities with the Polo-Box Domain of Polo-like Kinase 1; David Hymel and Terrence R. Burke, Jr.; ChemMedChem 2017; 12: 202-206. DOI: 10.1002/cmdc.201600574

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