Fmoc-L-Ser(TBDMS)-OH

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(t-butyl-dimethyl-silyl)-L-serine // Synonyms: Fmoc-Ser(TBDMS)-OH, Fmoc-Ser(BSi)-OH

  • Product code:FAA6510
  • CAS No.:146346-81-8
  • Formula:C24H30NO5Si
  • Molecular weight:441.60 g/mol

Starting at $195.00

Grouped product items
Qty Packing unit Price SKU
1 g
$195.00
FAA6510.0001
5 g
$715.00
FAA6510.0005
Safety Data Sheets
description

The TBDMS protecting group of the serine hydroxy function is more labile towards TFA than tBu and can selectively be cleaved in the presence of Boc/tBu with tetrabutylammonium fluoride in DMF. However, Fmoc is also being removed under these conditions!

references

Fischer P.M.; Tetrahedron Lett. 1992; 33: 7605.

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