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Fmoc-L-Cys(farnesyl)-OH
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-S-farnesyl-L-cysteine // Synonyms: (R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienylthio)propanoic acid, Fmoc-Cys(farnesyl)-OH
- Product code:FAA7890
- CAS No.:876312-47-9
- Formula:C33H41NO4S
- Molecular weight:547.75 g/mol
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references
Solid-phase synthesis of Biotin-S-Farnesyl-l-Cysteine, a surrogate substrate for isoprenylcysteine Carboxylmethyltransferase (ICMT). Graeme I. Stevenson, Sarah Yong, Gregory A. Fechner, Juliette Neve, Aaron Lock, Vicky M. Avery; Bioorg. Med. Chem. Lett. 2013; 23(20): 5671-5673. DOI: 10.1016/j.bmcl.2013.08.022
Chemical‐Biological Exploration of the Limits of the Ras De‐ and Repalmitoylating Machinery. Kristina Görmer, Marco Bürger, John A. W. Kruijtzer, Ingrid Vetter, Nachiket Vartak, Lucas Brunsveld, Philippe I. H. Bastiaens, Rob M. J. Liskamp, Gemma Triola, Herbert Waldmann; ChemBioChem 2012; 13(7): 1017-1023. DOI: 10.1002/cbic.201200078
Solid‐Phase Synthesis of Lipidated Ras Peptides Employing the Ellman Sulfonamide Linker. Gemma Triola, Marc Gerauer, Kristina Görmer, Lucas Brunsveld, Herbert Waldmann; Chem. Eur. J.2010; 16(31): 9585-9591.DOI: 10.1002/chem.201001642
Synthesis and application in SPPS of a stable amino acid isostere of palmitoyl cysteine. Elena Cini, Lucia Raffaella Lampariello, Manuela Rodriquez, Maurizio Taddei; Tetrahedron 2009; 65(4): 844-848.DOI: 10.1016/j.tet.2008.11.033
Influence of the Lipidation Motif on the Partitioning and Association of N-Ras in Model Membrane Subdomains. Katrin Weise, Gemma Triola, Luc Brunsveld, Herbert Waldmann, Roland Winter; J. Am. Chem. Soc. 2009; 131(4): 1557-1564. DOI: 10.1021/ja808691r
Efficient Solid‐Phase Lipopeptide Synthesis Employing the Ellman Sulfonamide Linker. Jose M. Palomo, Maria Lumbierres, Herbert Waldmann; Angew. Chem. Int. Ed. 2006; 45(3): 477-481. DOI: 10.1002/anie.200503298
Solid-phase synthesis of palmitoylated and farnesylated lipopeptides employing the fluoride-labile PTMSEL linker. Maria Lumbierres, Jose M. Palomo, Goran Kragol, Herbert Waldmann; Tetrahedron Lett. 2006; 47(16): 2671-2674. DOI: 10.1016/j.tetlet.2006.02.109
Solid‐Phase Synthesis of Lipidated Peptides. Maria Lumbierres, Jose M. Palomo, Goran Kragol, Sonja Roehrs, Oliver Müller, Herbert Waldmann; Chem. Eur. J. 2005; 11(24): 7405-7415. DOI: 10.1002/chem.200500476
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