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Fmoc-L-Asp(OEpe)-OH

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid beta-3-ethylpentyl ester // Synonyms: Fmoc-Asp(OEpe)-OH, N-alpha-Fmoc-(O-3-ethyl-pent-3-yl)aspartic acid, (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-((3-ethylpentan-3-yl)oxy)-4-oxobutanoic acid

Product code:FAA8235
CAS No.:1799418-01-1
Formula:C26H31NO6
Molecular weight:453,54 g/mol

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description

An excellent derivative for minimizing aspartimide formation during Fmoc SPPS of Asp-containing peptides. The bulky OEpe protecting group provides considerably more protection against the formation of aspartimide-related by-products than the commonly used OtBu group.

references

Patent EP 2 886 531 B1


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