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Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid beta-3-ethylpentyl ester // Synonyms: Fmoc-Asp(OEpe)-OH, N-alpha-Fmoc-(O-3-ethyl-pent-3-yl)aspartic acid, (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-((3-ethylpentan-3-yl)oxy)-4-oxobutanoic acid
|Molecular weight:||453,54 g/mol|
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An excellent derivative for minimizing aspartimide formation during Fmoc SPPS of Asp-containing peptides. The bulky OEpe protecting group provides considerably more protection against the formation of aspartimide-related by-products than the commonly used OtBu group.
Patent EP 2 886 531 B1
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