Fmoc-L-Tyr(cHx)-OH

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-cyclohexyl-L-tyrosine // Synonyms: Fmoc-Tyr(cHx)-OH, N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-cyclohexyl-L-tyrosine, N-alpha-(9-Fluorenylmethyloxycarbonyl)-4-cyclohexyloxy-L-phenylalanine, (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(cyclohexyloxy)phenyl)propanoic acid

Art-No. :FAA8245
CAS-No. :93298-85-2
Formula :C30H31NO5
Molecular weight :485,58 g/mol
Grouped product items
Qty Weight Price SKU
Please inquire Please inquire Please inquire FAA8245.0000
description
This building block can be used in Boc/Bzl SPPS. cHx can be removed by HF, but is stable towards TFA/DCM (1:1) for 24h. It can be used in Fmoc/tBu SPPS for peptide mimetics at the position of tyrosine.

Related CAS number: 67521-57-7 (DCHA free building block)

references
Solid phase synthesis of tyrosine-containing histone fragments; E. Giralt, D. Andreu, P. Miro and E. Pedroso; Tetrahedron 1983; 39: 3185-3188. doi: https://doi.org/10.1016/s0040-4020(01)91564-9

Convergent solid phase peptide synthesis-III; E. Giralt, R. Eritja, E. Pedroso, C. Granier and J. Van Rietschoten; Tetrahedron 1986; 42: 691-698. doi: https://doi.org/10.1016/s0040-4020(01)87472-x

Convergent solid phase peptide synthesis vi : synthesis by the fmoc procedure with a modified protocol of two protected segments, sequence 5-17 and 18-31 of the neurotoxin ii of the scorpion andr octonus australis hector; J. M. Sabatier, M. Tessier-Rochat, C. Granier, J. Van Rietschoten, E. Pedroso, A. Grandas, F. Albericio and E. Giralt; Tetrahedron 1987; 43: 5973-5980. doi: https://doi.org/10.1016/s0040-4020(01)87803-0

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