Fmoc-L-Lys(iNoc)-OH

Chemical name: N-alpha-(9-Fluorenylmethoxycarbonyl)-N-epsilon-pyridylmethoxycarbonyl-L-lysine, Fmoc-L-Lys(isonicotinyloxycarbonyl)-OH // Synonyms: Fmoc-Lys(iNoc)-OH

  • Product code:FAA8775
  • CAS No.:1459694-90-6
  • Formula:C28H29N3O6
  • Molecular weight:503.56 g/mol
  • Purity :min. 98%
  • Enantiomeric Purity:min. 99,7%

Starting at $140.40

Grouped product items
Qty Packing unit Price SKU
500 mg
$140.40
FAA8775.0500
1 g
$218.40
FAA8775.1000
5 g
$780.00
FAA8775.5000
25 g
$3,120.00
FAA8775.9025
description

This orthogonally side-chain protected Lysine is stable to most reagents used in peptide synthesis. The isonicotinyloxycarbonyl (iNoc)-group can be removed under mild reducing conditions like Zn/AcOH, Pd/C/H2, SmI2 in aq. DMF etc. Isomeric purity >99.9%.


references

Isonicotinyloxycarbonyl a novel amino protecting group for peptide synthesis; D. F. Veber, W. J. Paleveda, Y. C. Lee, R. Hirschmann; J. Org. Chem. 1977; 42(20): 3286-3288. https://doi.org/10.1021/jo00440a018.

Total Synthesis and Structural Characterization of Caveolin-1; H. Hojo, T. Takei, Y. Asahina, N. Okumura, T. Takao, M. So, I. Suetake, T. Sato, A. Kawamoto, Y. Hirabayashi; Angew. Chem. Int. Ed. 2021; 60(25): 13900-13905. https://doi.org/10.1002/anie.202100826.

Chemoenzymatic Synthesis of the Immunoglobulin Domain of Tim-3 Carrying a Complex-Type N-Glycan by Using a One-pot Ligation; Y. Asahina, S. Kamitori, T. Takao, N. Nishi, H. Hojo; Angew. Chem. Int. Ed. 52(37): 9733-9737. https://doi.org/10.1002/anie.201303073.

Bulk or large quantity order?

Do you need larger quantities for your development or production?

Do you need further information about this product?

get in contact

Quick contact

Please send me more information about

We found other products you might like!