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Chemical name: (S)-2-amino-6-(1-carboxyethylamino)-4,4,5,5-tetradeuterohexanoic acid // Synonyms: epsilon-N-carboxyethyl-[4,4,5,5-D4]-L-lysine (mixture of two diastereoisomers)
|Molecular weight:||222,27 g/mol|
Maillard Reaction Products (MRPs) are indicators for the heat treatment of food, as well as markers of nutritional quality. They also appear naturally in the human body as so-called Advanced Glycation End Products (AGEs). As such, they are indicators for body health and disease processes, including inflammation, diabetes, cancer and ageing. Consequently, AGEs gained broad attention in cosmetics, biochemistry, food, and pharmaceutical applications.
This material is supplied as a salt containing varying contents of the acid counterion. The net content of each batch is specified in the respective certificate of analysis.
N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins; M. U. Ahmed, E. Brinkmann Frye, T. P. Degenhardt, S. R. Thorpe and J. W. Baynes; The Biochemical journal 1997; 324 ( Pt 2): 565-70. https://doi.org/10.1042/bj3240565
Carboxyethyllysine in a protein: native carbonyl reductase/NADP(+)-dependent prostaglandin dehydrogenase; M. Krook, D. Ghosh, R. Stromberg, M. Carlquist and H. Jornvall; Proc Natl Acad Sci U S A 1993; 90: 502-6. https://doi.org/10.1073/pnas.90.2.502
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