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Chemical name: Glyoxal-hydroimidazolone isomer // Synonyms: (S)-2-amino-5-(4-oxo-4,5-dihydro-1H-imidazol-2-ylamino)pentanoic acid
|Molecular weight:||214,22 g/mol|
Maillard reaction product (MRP) are indicators for heat treatment of food. They are used as marker of the nutritional quality of food.
G-H1 is one of hydroimidazolone isomers derived from glyoxal and arginine residues.
Degradation products of proteins damaged by glycation, oxidation and nitration in clinical type 1 diabetes; N. Ahmed, R. Babaei-Jadidi, S. K. Howell, P. J. Beisswenger and P. J. Thornalley; Diabetologia 2005; 48: 1590-603. https://doi.org/10.1007/s00125-005-1810-7
Proteomic analysis of arginine adducts on glyoxal-modified ribonuclease; W. E. Cotham, T. O. Metz, P. L. Ferguson, J. W. Brock, D. J. Hinton, S. R. Thorpe, J. W. Baynes and J. M. Ames; Mol Cell Proteomics 2004; 3: 1145-53. https://doi.org/10.1074/mcp.M400002-MCP200
Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry; P. J. Thornalley, S. Battah, N. Ahmed, N. Karachalias, S. Agalou, R. Babaei-Jadidi and A. Dawnay; The Biochemical journal 2003; 375: 581-92. https://doi.org/10.1042/BJ20030763
Assay of advanced glycation endproducts (AGEs): surveying AGEs by chromatographic assay with derivatization by 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and application to Nepsilon-carboxymethyl-lysine- and Nepsilon-(1-carboxyethyl)lysine-modified albumin; N. Ahmed, O. K. Argirov, H. S. Minhas, C. A. Cordeiro and P. J. Thornalley; The Biochemical journal 2002; 364: 1-14. https://doi.org/10.1042/bj3640001
Chromatographic assay of glycation adducts in human serum albumin glycated in vitro by derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and intrinsic fluorescence; N. Ahmed and P. J. Thornalley; The Biochemical journal 2002; 364: 15-24. https://doi.org/10.1042/bj3640015
Isolation and characterization of advanced glycation end products derived from the in vitro reaction of ribose and collagen; R. G. Paul, N. C. Avery, D. A. Slatter, T. J. Sims and A. J. Bailey; The Biochemical journal 1998; 330 ( Pt 3): 1241-8. https://doi.org/10.1042/bj3301241
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