Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying though a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.Continue to Iris Biotech GmbHSend request to US distributor
Chemical name: 2-((S)-4-amino-4-carboxybutylamino)-4-((S)-5-amino-5-carboxypentyl)-1H-imidazo[4,5-b]pyridin-4-ium trifuoroacetic acid salt // Synonyms: Pentosidine trifluoroacetic acid salt
|CAS No.:||124505-87-9 net|
|Molecular weight:||379,43 g/mol|
Maillard reaction product (MRP) are indicators for heat treatment of food. They are used as marker of the nutritional quality of food. In pentosidine arginine and lysine have been crosslinked by a pentose. It is used as marker in aging and diseases. The fluorescence properties of the crosslink makes it easily detectable via UV in HPLC.
A sensitive and specific HPLC method for the determination of total pentosidine concentration in plasma; D. Slowik-Zylka, K. Safranow, V. Dziedziejko, H. Bukowska, K. Ciechanowski and D. Chlubek; J Biochem Biophys Methods 2004; 61: 313-29. https://doi.org/10.1016/j.jbbm.2004.06.002
Early glycation products produce pentosidine cross-links on native proteins. novel mechanism of pentosidine formation and propagation of glycation; P. Chellan and R. H. Nagaraj; J Biol Chem 2001; 276: 3895-903. https://doi.org/10.1074/jbc.M008626200
Cell-associated pentosidine as a marker of aging in human diploid cells in vitro and in vivo; D. R. Sell, M. Primc, I. A. Schafer, M. Kovach, M. A. Weiss and V. M. Monnier; Mechanisms of Ageing and Development 1998; 105: 221-240. https://doi.org/10.1016/s0047-6374(98)00090-6
Detection and quantification of pentosidine in foods; T. Henle, U. Schwarzenbolz and H. Klostermeyer; Zeitschrift fr Lebensmitteluntersuchung und -Forschung A 1997; 204: 95-98. https://doi.org/10.1007/s002170050043
Identification of pentosidine as a native structure for advanced glycation end products in beta-2-microglobulin-containing amyloid fibrils in patients with dialysis-related amyloidosis; T. Miyata, S. Taneda, R. Kawai, Y. Ueda, S. Horiuchi, M. Hara, K. Maeda and V. M. Monnier; Proc Natl Acad Sci U S A 1996; 93: 2353-8. https://doi.org/10.1073/pnas.93.6.2353
Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo; D. G. Dyer, J. A. Blackledge, S. R. Thorpe and J. W. Baynes; Journal of Biological Chemistry 1991; 266: 11654-11660.
Mechanism of formation of the Maillard protein cross-link pentosidine. Glucose, fructose, and ascorbate as pentosidine precursors; S. K. Grandhee and V. M. Monnier; Journal of Biological Chemistry 1991; 266: 11649-11653.
End-stage renal disease and diabetes catalyze the formation of a pentose-derived crosslink from aging human collagen; D. R. Sell and V. M. Monnier; J Clin Invest 1990; 85: 380-4. https://doi.org/10.1172/JCI114449
Structure elucidation of a senescence cross-link from human extracellular matrix. Implication of pentoses in the aging process; D. R. Sell and V. M. Monnier; J Biol Chem 1989; 264: 21597-602.
Do you need larger quantities for your development or production?
Please send me more information about