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Chemical name: S-(2-Succinyl)-L-cysteine // Synonyms: S-(1,2-dicarboxyethyl)-L-cysteine, (R)-2-(2-amino-2-carboxyethylthio)succinic acid
|CAS No. :||547764-73-8|
|Molecular weight:||237,23 g/mol|
2-SC has been identified as a chemical modification in tissue proteins and id formed by a Michael addition of cysteine to fumarate at physiological pH.
S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate; N. L. Alderson, Y. Wang, M. Blatnik, N. Frizzell, M. D. Walla, T. J. Lyons, N. Alt, J. A. Carson, R. Nagai, S. R. Thorpe and J. W. Baynes; Archives of biochemistry and biophysics 2006; 450: 1-8. https://doi.org/10.1016/j.abb.2006.03.005
Optical Resolution of (RS)-Mercaptosuccinic Acid and Syntheses of Four Stereoisomers of 2-Amino-3-1(1,2-dicarboxyethyl)sulfanyl)propanoic Acid; T. Shiraiwa, M. Ohkubo, M. Kubo, H. Miyazaki, M. Takehata, H. Izawa, K. Nakagawa and H. Kurokawa; Chemical & Pharmaceutical Bulletin 1998; 46: 1364-1369. https://doi.org/10.1248/cpb.46.1364
(2R), (1'R) and (2R), (1'S)-2-amino-3-(1,2-dicarboxyethylthio)propanoic acids from Amanita pantherina. Antagonists of N-methyl-D-aspartic acid (NMDA) receptors; S. Fushiya, Q. Q. Gu, K. Ishikawa, S. Funayama and S. Nozoe; Chem Pharm Bull (Tokyo) 1993; 41: 484-6. https://doi.org/10.1248/cpb.41.484
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