H-L-Tyr(All)-OH

Chemical name: O-Allyl-L-tyrosine // Synonyms: O-Allyl-tyrosine, Tyr(All)

Art-No.:HAA7435
Cas-no.:107903-42-4
Formula:C12H15NO3
Molecular weight:221.25 g/mol
Grouped product items
Product variant
250 mg
$120.15
HAA7435.0250
500 mg
$216.00
HAA7435.0500
1 g
$337.50
HAA7435.0001
5 g
$1,201.50
HAA7435.0005
description
This non-canonical amino acid can be incorporated into proteins using mutant pyrrolysyl-tRNA synthetasetRNAPylCUA pairs and can be used e.g. to identify protein tyrosine phosphatases.

references
Proteomic Identification of Protein Tyrosine Phosphatase and Substrate Interactions in Living Mammalian Cells by Genetic Encoding of Irreversible Enzyme Inhibitors; Hongting Tang, Zhen Dai, Xuewen Qin, Wenkang Cai, Liming Hu, Yujia Huang, Wenbing Cao, Fan Yang, Chu Wang, Tao Liu; J. Am. Chem. Soc. 2018; 140(41): 13253-13259. DOI: 10.1021/jacs.8b06922.

Exploring the potential impact of an expanded genetic code on protein function; Han Xiao, Fariborz Nasertorabi, Sei-hyun Choi, Gye Won Han, Sean A. Reed, Raymond C. Stevens, and Peter G. Schultz; PNAS 2015; 112(22): 6961-6966. DOI: 10.1073/pnas.1507741112.

Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes; Yan-Jiun Lee, Yadagiri Kurra, Yanyan Yang, Jessica Torres-Kolbus, Alexander Deiters, Wenshe R. Liu; Chem. Commun. 2014; 50: 13085-13088. DOI: 10.1039/C4CC06435F.

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