H-L-Trp(5-F,6-Br)-OH

Chemical name: 5-Fluoro-6-bromo-L-tryptophan // Synonyms: (S)-2-amino-3-(5-fluoro-6-bromoindolyl)propionic acid, (S)-2-amino-3-(5-fluoro-6-bromo-1H-indol-3-yl)propionic acid, H-Trp(5-F,6-Br)-OH

  • Product code:HAA8910
  • Formula:C11H10BrFN2O2
  • Molecular weight:301.11 g/mol

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references

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Suche nach einem n-Hal-Trp in einer Peptidstruktur:

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Hubert Chen, David Allen Annis, Yong Chang, Manuel Aivado, Karen Olson, Chris J. Viau; Aileron Therapeutics, Inc., USA 2016)


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Proteomic Analysis Provides Insights on Venom Processing in Conus textile. Lemmuel L. Tayo, Bingwen Lu, Lourdes J. Cruz, John R. Yates; J. Proteome Res. 2010; 9(5): 2292-2301. DOI:

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Thermodynamic and Computational Studies on the Binding of p53‐Derived Peptides and Peptidomimetic Inhibitors to HDM2. Anja Grässlin, Celine Amoreira, Kim K. Baldridge, John A. Robinson; ChemBioChem 2009: 10(8): 1360-136. https://doi.org/10.1002/cbic.200900008


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The central valine concept provides an entry in a new class of non peptide inhibitors of the p53-MDM2 interaction.

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