AEBSF*HCl

Chemical name: 4-(2-Aminoethyl)-benzenesulfonylfluoride hydrochloride // Synonyms: 4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride, AEBSF HCl, Pefabloc SC

Product code:LS-3355
CAS No.:30827-99-7
Formula:C8H10FNO2S*HCl
Molecular weight:203,23*36,45 g/mol
Grouped product items
Qty Packing unit Price SKU
500 mg
$135.00
LS-3355.0005
Safety Data Sheets
description
Specific, irreversible inhibitor of serine proteases. Ideal substitute for PMSF and DFP with a comparable inhibitory activity. Advantages compared to PMSF: non-toxic, excellent blocker of thrombin activity in serum or plasma.

Possible Targets: Chymotrypsin, Kallikrein, Plasmin, Trypsin,Thrombin

references
P. Megyeri, K. M. Pabst & M. J. Pabst (1995) Serine protease inhibitors block priming of monocytes for enhanced release of superoxide. Immunology, 86, 629635.

M. Citron, T. S. Diehl, A. Capell, C. Haass, D. B. Teplow, and D. J. Selkoe (1996) Inhibition of Amyloid b-Protein Production in Neural Cells by the Serine Protease Inhibitor

AEBSF. Neuron, 17, 171-179.

Inhibition of amyloid beta-protein production in neural cells by the serine protease inhibitor AEBSF; M. Citron, T. S. Diehl, A. Capell, C. Haass, D. B. Teplow and D. J. Selkoe; Neuron 1996; 17: 171-9. doi:https://doi.org/10.1016/S0896-6273(00)80290-1

Serine protease inhibitors block priming of monocytes for enhanced release of superoxide; P. Megyeri, K. M. Pabst and M. J. Pabst; Immunology 1995; 86: 629-35.

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