Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
USD
Quick contact
Please send me more information about
Leupeptin Hemisulfate
Chemical name: N-Acetyl-L-leucyl-L-leucyl-L-argininal hemisulfate salt // Synonyms: Acetyl-Leu-Leu-Arg-al
- Product code:LS-3900
- CAS No.:103476-89-7
- Formula:C20H38N6O4 * 1/2H2SO4
- Molecular weight:475.59 g/mol
Starting at Please inquire
description
A potent, reversible inhibitor of serine and cysteine proteases that shows little to no inhibitory activity against pepsin, cathepsins A and D and alpha-chymotrypsin.
references
Active and inactive forms of the transition-state analog protease inhibitor leupeptin: explanation of the observed slow binding of leupeptin to cathepsin B and papain; R. M. Schultz, P. Varma-Nelson, R. Ortiz, K. A. Kozlowski, A. T. Orawski, P. Pagast and A. Frankfater; J Biol Chem 1989; 264: 1497-507.
Inhibition of thrombin-induced platelet activation by leupeptin. Implications for the participation of calpain in the initiation of platelet activation; L. F. Brass and S. J. Shattil; J Biol Chem 1988; 263: 5210-6.
Successful treatment of murine muscular dystrophy with the proteinase inhibitor leupeptin; J. H. Sher, A. Stracher, S. A. Shafiq and J. Hardy-Stashin; Proc Natl Acad Sci U S A 1981; 78: 7742-4.
Letter: A thermolysin inhibitor produced by Actinomycetes: phospholamidon; H. Suda, T. Aoyagi, T. Takeuchi and H. Umezawa; The Journal of antibiotics 1973; 26: 621-3.
Inhibition of tumorigenesis in mouse skin by leupeptin, a protease inhibitor from Actinomycetes; M. Hozumi, M. Ogawa, T. Sugimura, T. Takeuchi and H. Umezawa; Cancer Res 1972; 32: 1725-8.
Bulk or large quantity order?
Do you need larger quantities for your development or production?
Do you need further information about this product?
get in contact
Related Products
Related news
-
News Life Sciences Product FocusProtease Inhibitors
Protease inhibitors are molecules that inhibit protease function by binding either reversibly or irreversibly to the enzyme.
view details
We found other products you might like!
