Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying though a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.Continue to Iris Biotech GmbHSend request to US distributor
Chemical name: N-Acetyl-L-leucyl-L-leucyl-L-argininal hemisulfate salt // Synonyms: Acetyl-Leu-Leu-Arg-al
|Formula:||C20H38N6O4 * 1/2H2SO4|
|Molecular weight:||475,59 g/mol|
A potent, reversible inhibitor of serine and cysteine proteases that shows little to no inhibitory activity against pepsin, cathepsins A and D and alpha-chymotrypsin.
Active and inactive forms of the transition-state analog protease inhibitor leupeptin: explanation of the observed slow binding of leupeptin to cathepsin B and papain; R. M. Schultz, P. Varma-Nelson, R. Ortiz, K. A. Kozlowski, A. T. Orawski, P. Pagast and A. Frankfater; J Biol Chem 1989; 264: 1497-507.
Inhibition of thrombin-induced platelet activation by leupeptin. Implications for the participation of calpain in the initiation of platelet activation; L. F. Brass and S. J. Shattil; J Biol Chem 1988; 263: 5210-6.
Successful treatment of murine muscular dystrophy with the proteinase inhibitor leupeptin; J. H. Sher, A. Stracher, S. A. Shafiq and J. Hardy-Stashin; Proc Natl Acad Sci U S A 1981; 78: 7742-4.
Letter: A thermolysin inhibitor produced by Actinomycetes: phospholamidon; H. Suda, T. Aoyagi, T. Takeuchi and H. Umezawa; The Journal of antibiotics 1973; 26: 621-3.
Inhibition of tumorigenesis in mouse skin by leupeptin, a protease inhibitor from Actinomycetes; M. Hozumi, M. Ogawa, T. Sugimura, T. Takeuchi and H. Umezawa; Cancer Res 1972; 32: 1725-8.
Do you need larger quantities for your development or production?
Please send me more information about