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Chemical name: N-(2-mercaptoethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide // Synonyms: Biotin-2-Mercaptoethylamine
|Molecular weight:||303,44 g/mol|
This biotin derivative bears a terminal sulfhydryl moiety. It can be used to prepare various biotinylated conjugates. Biotin can be subsequently detected e.g. via streptavidin or avidin.
A genetically Encoded, Phage-Displayed Cyclic-Peptide Library; X. S. Wang, P.-H. C. Chen. J. T. Hampton, J. M. Tharp, C. A. Reed, S. K. Das, D.-S. Wang, H. S. Hayatshahi, Y. Shen, J. Liu, W. R. Liu; Angew. Chem. Int. Ed. 2019; 58(44): 15904-15909. https://doi.org/10.1002/anie.201908713.
One step synthesis of monodisperse thiol-ene clickable polymer microspheres and application on biological functionalization; Y. Huang, J. Yuan, J. Tang, J. Yang, Z. Zeng; Eur. Polym. J. 2019; 110: 22-30. https://doi.org/10.1016/j.eurpolymj.2018.11.018.
A Bifunctional Spin Label for Ligand Recognition on Surfaces; M. A. Hollas, S. J. Webb, S. L. Flitsch, A. J. Fielding; Angew. Chem. Int. Ed. 2017; 56(32): 449-9453. https://doi.org/10.1002/anie.201703929.
Intracellular Delivery of Functional Proteins and Native Drugs by Cell-Penetrating Poly(disulfide)s; J. Fu, C. Yu, L. Li, S. Q. Yao; J. Am. Chem. Soc. 2015; 137(137): 12153-12160. https://doi.org/10.1021/jacs.5b08130.
A Chemoe-Enzymatic Approach for Site-Specific Modification of the RNA Cap; D. Schulz, J. M. Holstein, A. Rentmeister; Angew. Chem. Int. Ed. 2013; 52(30): 7874-7878. https://doi.org/10.1002/anie.201302874.
Polymer control of ligand display on gold nanoparticles for multimodal switchable cell targeting; F. Mastrotto, P. Caliceti, V. Amendola, S. Bersani, J. P. Magnusson, M. Meneghetti, G. Mantovani, C. Alexander, S. Salmaso; Chem. Commun. 2011; 47: 9846-9848. https://doi.org/10.1039/C1CC12654G.
Biochemical Assays of Immobilized Oligonucleotides with Mass Spectrometry; H. Tsubery, M. Mrksich; Langmuir 2008; 24(10): 5433-5438. https://doi.org/10.1021/la7040482.
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