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Chemical name: N-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide // Synonyms: Biotin-Methyltetrazine
|Molecular weight:||427,53 g/mol|
This biotin derivative bears a terminal methyltetrazine group. It can be used to prepare various biotinylated conjugates. Biotin can be subsequently detected e.g. via streptavidin or avidin. The methyltetrazine is reactive to trans-cyclooctenes.
Systemic Fluorescence Imaging of Zebrafish Glycans with Bioorthogonal Chemistry; P. A. Agarwal, B. J. Beahm, P. Shieh, C. R. Bertozzi; Angew. Chem. Int. Ed. 2015; 54(39): 11504-11510. https://doi.org/10.1002/anie.201504249.
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