Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying though a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.Continue to Iris Biotech GmbHSend request to US distributor
This biotin derivative bears a terminal azide group. It can be used to prepare various biotinylated conjugates via Click Chemistry. Biotin can be subsequently detected e.g. via streptavidin or avidin. Triazole-linked adducts are showen to be highly resistant to the ubiquitous hydrolytic enzyme biotinidase and to bind avidin with dissociation constants in the low pM range.
Probing biotin receptors in cancer cells with rationally designed fluorogenic squaraine dimers; K. T. Fam, M. Collot, A. S. Klymchenko; Chem. Sci. 2020; 11: 8240-8248. https://doi.org/10.1039/D0SC01973A.
Biotin-tagged fluorescent sensor to visualize ‘mobile’ Zn2+ in cancer cells; L. Fang, G. Trigiante, C. J. Kousseff, R. Crespo-Otero, M. P. Philpott, M. Watkinson; Chem. Commun. 2018; 54: 9619-9622. https://doi.org/10.1039/C8CC05425H.
Surface-enhanced Raman encoded polymer stabilized gold nanoparticles: Demonstration of potential for use in bioassays; T. L. Schiller, D. J. Keddie, I. Blakey, P. M. Fredericks; Eur. Polym. J. 2017; 87: 508-518. https://doi.org/10.1016/j.eurpolymj.2016.08.032.
A versatile platform for adding functional properties to amyloid fibrils; D. F. A. Fontaine, V. A. Ivancic, M. B. Reardon, N. D. Lazo, C. E. Jakobsche; Org. Biomol. Chem. 2017; 15: 8023-8027. https://doi.org/10.1039/C7OB02042B.
Heterocyclic acyl-phosphate bioisostere-based inhibitors of Staphylococcus aureus biotin protein ligase; W. Tieu, A. M. Jarrad, A. S. Paparella, K. A. Keeling, T. P. Soares da Costa, J. C. Wallace, G. W. Booker, S. W. Polyak, A. D. Abell; Bioorg. Med. Chem. Lett. 2014; 24(19): 4689-4693. https://doi.org/10.1016/j.bmcl.2014.08.030.
Triazole biotin: a tight-binding biotinidase-resistant conjugate; A. I. Germeroth, J. R. Hanna, R. Karim, F. Kundel, J. Lowther, P. G. N. Neate, E. A. Blackburn, M. A. Wear, D. J. Campopiano, A. N. Hulme; Org. Biomol. Chem. 2013; 11: 7700-7704. https://doi.org/10.1039/C3OB41837E.
A Photocleavable Rapamycin Conjugate for Spatiotemporal Control of Small GTPase Activity; N. Umeda, T. Ueno, C. Pohlmeyer, T. Nagano, T. Inoue; J. Am. Chem. Soc. 2011; 133(1): 12-14. https://doi.org/10.1021/ja108258d.
Do you need larger quantities for your development or production?
Please send me more information about