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Biotin-naphthylamine
Chemical name: N-(3-(5-aminonaphthalen-1-yl)propyl)biotinamide // Synonyms: Btn-Nap, N-(3-(5-aminonaphthalen-1-yl)propyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
- Product code:LS-4650
- CAS No.:2375201-60-6
- Formula:C23H30N4O2S
- Molecular weight:426.58 g/mol
Starting at $312.50
description
Reported as substrate for APEX2, an engineered ascorbate peroxidase that enables proximity-dependent labeling of proteins in living cells. Biotin-naphthylamine represents a novel probe with higher labeling reactivity towards proteins and nucleic acids. Btn-Nap could label both double-stranded and single-stranded DNA.
references
Expanding APEX2 Substances for Proximity-Dependent Labeling of Nucleic Acids and Proteins in Living Cells; Y. Zhou, G. Wang, L. Pengchong, T. Yue, J. Wang, P. Zou; Angew. Chem. Int. Ed. 2019; 58(34): 11763-11767. https://doi.org/10.1002/anie.201905949.
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