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Chemical name: trans-4-(maleimidomethyl)cyclohexane-1-carboxylic acid // Synonyms: 4-(maleimidomethyl)cyclohexane-1-carboxylic acid, Mal-AMCHC
|Molecular weight:||237,25 g/mol|
Mal-AMCHC is used as a linker in various applications. It is employed as an antibody-drug linker in approved cancer medication Kadcyla by Genentech/Roche and used as a linker in PCA-062 by Novartis, currently in clinical trials. It is also used in IMMU-132 by Immunomedics, currently in clinical trials.
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