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Chemical name: Potassium 8-azido-3,6-dioxaoctanoate // Synonyms: N3-O2Oc-OK, potassium 2-(2-azidoethoxy)ethoxyacetate, N3-AEEA K salt, N3-AEEAc*K, 8-azido-3,6-dioxaoctanoic acid potassium salt, potassium 2‐[2‐(2‐azidoethoxy)ethoxy]acetate, N3-Ado potassium salt
|CAS No.:||882518-90-3 net|
|Molecular weight:||39,10*188,16 g/mol|
Used as a linker to produce drug conjugates via Click-chemistry and in other applications.
Polymeric Phosphorylcholine−Camptothecin Conjugates Prepared by Controlled Free Radical Polymerization and Click Chemistry; Xiangji Chen, Samantha McRae, Sangram Parelkar and Todd Emrick; Bioconjugate Chem. 2009; 20(12): 2331-2341. DOI:10.1021/bc900339x;
Glycan-Targeted Virus-like Nanoparticles for Photodynamic Therapy; Jin-Kyu Rhee, Michael Baksh, Corwin Nycholat, James C. Paulson, Hiroaki Kitagishi, and M. G. Finn; Biomacromolecules 2012; 13(8): pp 2333–2338. DOI: 10.1021/bm300578p.
N-Methyl-N-phenylvinylsulfonamides for Cysteine-Selective Conjugation; Rong Huang, Zhihong Li, Yao Sheng, Jianghui Yu, Yue Wu, Yuexiong Zhan, Hongli Chen, and Biao Jiang; Org. Lett. 2018; 20(20): 6526–6529. DOI: 10.1021/acs.orglett.8b02849
Ciulli, Alessio; Testa, Andrea; Brit. UK Pat. Appl. 2018; GB 2554071 A 20180328.
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