Welcome to Iris Biotech
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Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying though a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.Continue to Iris Biotech GmbHSend request to US distributor
Isoacyl Dipeptides are used to increase the coupling efficiencies during Fmoc-SPPS. The acetylation of the hydroxyl group of a Boc-protected serine or threonine with an Fmoc-amino acid leads to the formation of depsipeptides in which the peptide chain contains an ester bond instead of an amide bond at the respective position. In analogy to pseudoprolines, this leads to a conformational disruption preventing aggregation. Even after cleavage from the Fmoc-SPPS resin, the depsipeptide benefits of increased solubility compared to the native peptide sequence, thus facilitating further purification.