Products with DBCO

Products with DBCO

In contrast to linear alkynes, cyclooctynes such as Dibenzoazacyclooctyne (DBCO), strongly react with azides via a 1,3-dipolar cycloaddition forming a triazole product. For this 2nd generation Click reaction, the so-called strain-promoted azide-alkyne cycloaddition (SPAAC), no copper catalysis is required. Thus, cyclooctynes allow to perform biorthogonal couplings to azide-bearing biomolecules in live cells or organisms such as C. elegans, zebrafish or mice. By substituting the cyclooctyne core structure, key properties such as cycloaddition kinetics, stability, solubility, and pharmacokinetics can be further tuned.

  1. Structure image for Halo-DBCO
    Halo-DBCO

    Product code: RL-3670

  2. Structure image for Biotin-DBCO
    Biotin-DBCO

    Product code: LS-4270

  3. Structure image for DBCO-SNAP
    DBCO-SNAP

    Product code: RL-4010

  4. Structure image for ICG-DBCO
    ICG-DBCO

    Product code: RL-2870

  5. Structure image for DBCO-COOH
    DBCO-COOH

    Product code: RL-2430

  6. Structure image for DBCO-NHS
    DBCO-NHS

    Product code: RL-2440

  7. Structure image for DBCO-PEG(36)-TFP
    DBCO-PEG(36)-TFP

    Product code: PEG6765

  8. Structure image for DBCO-mal
    DBCO-mal

    Product code: RL-2490

  9. Structure image for DBCO-PEG(36)-MAL
    DBCO-PEG(36)-MAL

    Product code: PEG6785

  10. Structure image for DBCO-C6-Alkyne
    DBCO-C6-Alkyne

    Product code: RL-4020

  11. New
  12. Structure image for DBCO-NH2
    DBCO-NH2

    Product code: RL-2120