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Trityl/TCP Resins
Resins functionalized with trityl linkers are highly acid sensitive, as the three phenyl rings stabilize the benzylic carbocation that is generated during cleavage. These cleavage conditions are so mild that only 1% of TFA is needed, and even less acidic protocols using 20% hexafluoroisopropanol (HFIP) are sufficient to cleave the products from the resin. Various trityl-based linkers exist with different substitutions on the trityl group that fine-tune the cleavage conditions and stability of the preloaded resin.
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H-D-Arg(Pbf)-2CT ResinProduct code: RAA1029
Particle size : 100-200 mesh
Starting at Please inquire
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H-D-Asp(OtBu)-2CT ResinProduct code: RAA1049
Particle size : 100-200 mesh
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Fmoc-L-Asp(2CT resin)-NH2Product code: RAA2610
Particle size : 100-200 mesh
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H-L-Cys(Clt)-2CT ResinProduct code: RAA1050
Particle size : 100-200 mesh
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H-L-Cys(Mmt)-2CT ResinProduct code: RAA1055
Particle size : 100-200 mesh
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Fmoc-L-Cys(Mmt resin)-NH2Product code: RAA2620
Particle size : 100-200 mesh
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H-D-Cys(Trt)-2CT ResinProduct code: RAA1060
Particle size : 100-200 mesh
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H-L-Dap(Boc)-2CT ResinProduct code: RAA1330
Particle size : 100-200 mesh
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H-L-Dap(Boc)-2CT ResinProduct code: RAA1331
Particle size : 200-400 mesh
Starting at Please inquire
