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Chemical name: (S)-3-(N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-t-butyloxycarbonyl-L-lysinyl)-2,2-dimethylthiazolidine-4-carboxylic acid
|Molecular weight:||611,75 g/mol|
Dipeptide building blocks for structure disruption, avoids aggregation and increases yield during peptide synthesis. Ring opening with 10% TFMSA/TFA.
Pascal Dumy, Michael Keller, Declan E. Ryan, Barbara Rohwedder, Torsten Wöhr, and Manfred Mutter; Pseudo-Prolines as a Molecular Hinge: Reversible Induction of cis Amide Bonds into Peptide Backbones; J. Am. Chem. Soc. 1997; 119: 918-925.
Torsten Wöhr, Franck Wahl, Adel Nefzi, Barbara Rohwedder, Tatsunori Sato, Xicheng Sun, and Manfred Mutter; Pseudo-Prolines as a Solubilizing, Structure-Disrupting Protection Technique in Peptide Synthesis; J. Am. Chem. Soc. 1996; 118: 9218-9227.
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