Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
USD
Quick contact
Please send me more information about
Photo-Benzoic acid
Chemical name: 4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzoic acid
- Product code:RL-2920
- CAS No.:85559-46-2
- Formula:C9H5F3N2O2
- Molecular weight:230.14 g/mol
Starting at $260.00
description
Electrophilic photo cross-linker. The carboxylic acid function can conjugate to nucleophiles like amines with standard condensation reaction conditions. The diazirine ring will dismiss N2 under illumination of UV light and the remaining carbene will undergo insertion and addition reaction with any neighboring molecules and irreversibly form a covalent bond.
Shipping with dry ice required!
Transport costs depend on destination.
Please inquire!
references
Cross-linking chemistry and biology: development of multifunctional photoaffinity probes. Takenori Tomohiro, Makoto Hashimoto, Yasumaru Hatanaka; Chem. Record 2005; 5(6): 385-395. DOI: 10.1002/tcr.20058
Recent Progress in Diazirine-Based Photoaffinity Labeling. Makoto Hashimoto, Yasumaru Hatanaka; Eur. J. Org. Chem. 2008; 2513-2523. DOI: 10.1002/ejoc.200701069
Endeavors to Make the Photophore, Diazirine Easy to Use. Yutaka Sadakane; Yakugaku Zasshi 2007; 127(10): 1693-1699. DOI: org/10.1248/yakushi.127.1693
Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis. James R. Hill, Avril A. B. Robertson; J. Med. Chem. 2018; 61: 6945−6963. DOI: 10.1021/acs.jmedchem.7b01561.
Bulk or large quantity order?
Do you need larger quantities for your development or production?
Do you need further information about this product?
get in contact
Related Products
Broschures & Flyers
Related news
-
News Amino Acids Building BlocksPhotoaffinity Labeling by Diazirine Building Blocks
Discover our diazirine-substituted building blocks suitable for the analysis of protein-protein and RNA-protein interactions via proximity
view details
We found other products you might like!
