Mal-N-Boc-Aeg-NHS

Chemical name: N-(t-butoxycarbonyl)-N-(2-(maleinimido)ethyl)glycine N-Hydroxysuccinimidyl ester // Synonyms: 2,5-dioxopyrrolidin-1-yl N-(tert-butoxycarbonyl)-N-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)glycinate, Mal-CH2CH2-N(Boc)-CH2-CO-NHS, Boc-N-(Mal-Et)-Gly-NHS

Product code:RL-3430
Formula:C17H21N3O8
Molecular weight:395,37 g/mol
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references

Long-Term Stabilization of Maleimide–Thiol Conjugates. Shaun D. Fontaine, Ralph Reid, Louise Robinson, Gary W. Ashley, Daniel V. Santi; Bioconjugate Chem. 2015; 26(1): 145-152. DOI: 10.1021/bc5005262

Mild Method for Succinimide Hydrolysis on ADCs: Impact on ADC Potency, Stability, Exposure, and Efficacy. L. Nathan Tumey, Manoj Charati, Tao He, Eric Sousa, Dangshe Ma, Xiaogang Han, Tracey Clark, Jeff Casavant, Frank Loganzo, Frank Barletta, Judy Lucas, Edmund I. Graziani; Bioconjugate Chem. 2014; 25(10): 1871-1880. DOI: 10.1021/bc500357n

Covalent Modification of Biomolecules through Maleimide-Based Labeling Strategies. Kévin Renault, Jean Wilfried Fredy, Pierre-Yves Renard, Cyrille Sabot; Bioconjugate Chem. 2018; 29(8): 2497-2513. DOI: 10.1021/acs.bioconjchem.8b00252

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