Chemical name: 4-((2-(t-Butyloxycarbonylamino)ethyl)disulfaneyl)benzyl p-nitrophenylcarbonate // Synonyms: tert-butyl (2-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)disulfaneyl)ethyl)carbamate

  • Product code:RL-3570
  • CAS No.:2576471-38-8
  • Formula:C21H24N2O7S2
  • Molecular weight:480.55 g/mol

Starting at Please inquire

Grouped product items
Qty Packing unit Price SKU
Please inquire Please inquire Please inquire RL-3570.0000

Boc-protected self-immolative linker for traceless bioconjugation. The p-nitrophenylcarbonate activating group reacts preferably with amine and other nucleophlies.


Disulfide-Based Self-Immolative Linkers and Functional Bioconjugates for Biological Applications; Z. Deng, J. Hu and S. Liu; Macromol Rapid Commun 2020; 41: e1900531.

Reduction-Triggered Transformation of Disulfide-Containing Micelles at Chemically Tunable Rates; Z. Deng, S. Yuan, R. X. Xu, H. Liang and S. Liu; Angew Chem Int Ed Engl 2018; 57: 8896-8900.

Intracellular Delivery of Native Proteins Facilitated by Cell-Penetrating Poly(disulfide)s; L. Qian, J. Fu, P. Yuan, S. Du, W. Huang, L. Li and S. Q. Yao; Angew Chem Int Ed Engl 2018; 57: 1532-1536.

Thiolytically cleavable dithiobenzyl urethane-linked polymer-protein conjugates as macromolecular prodrugs: reversible PEGylation of proteins; S. Zalipsky, N. Mullah, C. Engbers, M. U. Hutchins and R. Kiwan; Bioconjug Chem 2007; 18: 1869-78.

Bulk or large quantity order?

Do you need larger quantities for your development or production?

Do you need further information about this product?

get in contact

Quick contact

Please send me more information about

We found other products you might like!