Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying though a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.Continue to Iris Biotech GmbHSend request to US distributor
Chemical name: N-(Mesyl)-4,8-diazacyclononyne hydrochloride // Synonyms: 2,3,4,5,6,9-hexahydro-1-(methylsulfonyl)- 1H-1,5-Diazonine hydrochloride, N-methanesulfonyl-4,8-diazacyclononyne hydrochloride, NH,NMs-DACN, CAS-Nr. 2331322-15-5 (net)
|Molecular weight:||202,27*36,46 g/mol|
Iris Biotech offers a variety of substituted 4,8-diazacyclononynes. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. The reactivity of an alkyne heavily depends on the electronic and steric characteristics of the substituents as well as structural strain. In comparison to nonbent acyclic alkynes, cyclononyne alkynes show remarkably high reactivity. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. In comparison to cyclooctynes, DACNs possess high thermal and chemical stability along with comparable click reactivity. In comparison to NTs-DACNs, NMs-DACNs show higher water solubility.
Synthesis of NMs-DACN: Small and Hydrophilic Click Reaction Device; Y. Kawasaki, Y. Yamanaka, Y. Seto, K. Igawa, K. Tomooka; Chem. Lett. 2019; 48: 495-497. https://doi.org/10.1246/cl.190026.
Do you need larger quantities for your development or production?
Please send me more information about