Chemical name: N-(4-(((2-amino-9H-purin-6-yl)oxy)methyl)benzyl)-4,7,10,13,16-pentaoxanonadec-18-ynamide // Synonyms: Alkyne-PEG(5)-Benzylguanine, Alkyne-PEG-Benzylguanine, Alkyne-PEG-SNAP, Alkyne-PEG(5)-BG, Alkyne-PEG-BG

  • Product code:RL-3940
  • Formula:C27H36N6O7
  • Molecular weight:556.62 g/mol

Starting at $390.00

Grouped product items
Qty Packing unit Price SKU
5 mg
25 mg

Alkyne conjugated benzylguanine (BG). The BG moiety reacts specifically and rapidly with the so-called SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation.

The additional PEG moiety increases overall solubility.


Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand; J. Broichhagen, A. Damijonaitis, J. Levitz, K. R. Sokol, P. Leippe, D. Konrad, E. Y. Isacoff, D. Trauner; ACS Cent Sci. 2015; 1(7): 383-93.

A Semisynthetic Fluorescent Sensor Protein for Glutamate; M. A. Brun, K.-T. Tan, R. Griss, A. Kielkowska, L. Reymond, K. Johnsson; J. Am. Chem. Soc. 2012; 134(18): 7676-7678.

Fura-2FF-based calciumindicator for proteinlabeling; A. A. Ruggiu, M. Bannwarth, K. Johnsson; Org. Biomol. Chem. 2010; 8: 3398-3401.

Indo-1 Derivatives for Local Calcium Sensing; M. Bannwarth, I. R. Corrêa Jr., M. Sztretye, S. Pouvreau, C. Fellay, A. Aebischer, L. Royer, E. Ríos, K. Johnsson; ACS Chem. Biol. 2009; 4(3): 179-190.

Caged Substrates for Protein Labeling and Immobilization; S. Banala, A. Arnold, K. Johnsson; ChemBioChem 2008; 9(1): 38-41.

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