DBCO-SNAP

Synonyms: DBCO-BG, DBCO-Benzylguanine

  • Product code:RL-4010
  • Formula:C34H31N7O3
  • Molecular weight:585.67 g/mol

Starting at $390.00

Grouped product items
Qty Packing unit Price SKU
5 mg
$390.00
RL-4010.0005
25 mg
$1,560.00
RL-4010.0025
description

Alkyne conjugated benzylguanine (BG). The BG moiety reacts specifically and rapidly with the so-called SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation.


references

Reference:

Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors; J. Levitz, J. Broichhagen, P. Leippe, D. Konrad, D. Trauner, E. Y. Isacoff; PNAS 2017; 114(17): E3546-E3554. https://doi.org/10.1073/pnas.1619652114

Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand; J. Broichhagen, A. Damijonaitis, J. Levitz, K. R. Sokol, P. Leippe, D. Konrad, E. Y. Isacoff, D. Trauner; ACS Cent Sci. 2015; 1(7): 383-93. https://doi.org/10.1021/acscentsci.5b00260


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