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DBCO-C6-Alkyne
Chemical name: N-(propargylamidoadipoyl)-dibenzoazacyclooctyne
- Product code:RL-4020
- Formula:C24H22N2O2
- Molecular weight:370.45 g/mol
Starting at $357.50
description
Click-cross-linker bearing two alkyne functions with orthogonal reactivity. Depending on the reaction conditions the one or the other alkyne function can react first with azido groups. In a consecutive step, the formerly protected alkyne function can react with a second azido group bearing reagent.
references
Transient Protection of Strained Alkynes from Click Reaction via Complexation with Copper; S. Yoshida, Y. Hatakeyama, K. Johmoto, H. Uekusa, T. Hosoya; J. Am. Chem. Soc. 2014; 136(39): 13590−13593. https://doi.org/10.1021/ja507660x
A facile preparation of functional cycloalkynes via an azide-to-cycloalkyne switching approach; S. Yoshida, T. Kuribara, H. Ito, T. Meguro, Y. Nishiyama, F. Karaki, Y. Hatakeyama, Y. Koike, I. Kiib, T. Hosoy; Chem. Commun. 2019; 55: 3556-3559. https://doi.org/10.1039/C9CC01113G
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