pNCO-SS-OpNC

Chemical name: disulfanediylbis(ethane-2,1-diyl) bis(4-nitrophenyl) bis(carbonate)

  • Product code:RL-4160
  • CAS No.:1435972-52-3
  • Formula:C18H16N2O10S2
  • Molecular weight:484.45 g/mol

Starting at $218.75

Grouped product items
Qty Packing unit Price SKU
100 mg
$218.75
RL-4160.0100
250 mg
$437.50
RL-4160.0250
description

A symmetric disulfide-based self-immolative linker.

references

Influence of Linkers within Stimuli-Responsive Prodrugs on Cancer Therapy: A Case of Five Doxorubicin Dimer-Based Nanoparticles; Q. Wang, C. Wang, S. Li, Y. Xiong, H. Wang, Z. Li, J. Wan, X. Yang, Z. Li; Chem. Mater. 2022; 34(5): 2085-2097. https://doi.org/10.1021/acs.chemmater.1c03346

De Novo design of a humanized antiCD33 antibody-oridonin conjugate for acute myeloid leukemia therapy; H. Feng, Y. Liu, M. Zhang, R. Liu, J. Wang, W. Wang, P. He, P. Zhang, F. Niu; Biochem. Biophys. Res. Commun. 2022; 629: 152-158. https://doi.org/10.1016/j.bbrc.2022.09.032

Engineered Cell-Penetrating Peptides for Mitochondrion-Targeted Drug Delivery in Cancer Therapy; Q. Xiao, X. Dong, F. Yang, S. Zhou, M. Xiang, L. Lou, S. Q. Yao, L. Gao; Chem. Eur. J. 2021; 27(59): 14721-14729. https://doi.org/10.1002/chem.202102523

Cell-Penetrating Mitochondrion-Targeting Ligands for the Universal Delivery of Small Molecules, Proteins and Nanomaterials; Q. Xiao, W. Du, X. Dong, S. Du, S. Y. Ong, G. Tang, C. Zhang, F. Yang, L. Li, L. Gao, S. Q. Yao; Chem. Eur. J. 2021; 27(47): 12207-12214. https://doi.org/10.1002/chem.202101989

Activation of lysine-specific demethylase 1 inhibitor peptide by redox-controlled cleavage of a traceless linker; Y. Amano, N. Umezawa, S. Sato, H. Watanabe, T. Umehara, T. Higuchi; Bioorg. Med. Chem. 2017; 25(3): 1227-1234. https://doi.org/10.1016/j.bmc.2016.12.033


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