Fmoc-L-Cys(S-tBu)-SEA-PS resin

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-S-(t-butylthio)-L-cysteine bis(2-sulfanylethyl)amino-trityl-polystyrene

Art-No.:SEA2005
Particle size:200-400 mesh
DVB crosslinking:1% DVB
Loading:0.1 - 0.2 mmol/g
Grouped product items
Product variant
1 g
$729.00
SEA2005.0001
5 g
$1,822.50
SEA2005.0005
10 g
$2,700.00
SEA2005.0010
25 g
$4,758.75
SEA2005.0025
description
New resin for the synthesis of long peptides and mini-proteins. An elegant method of forming peptide thioesters as fragments for the synthesis of mini proteins with natural peptide ligation techniques (NPL).

references
L. Raibaut, N. Ollivier, O. Melnyk; Sequential native peptide ligation strategies for total chemical protein synthesis; Chem. Soc. Rev. 2012; 41: 7001-7015; DOI:

10.1039/c2cs35147a.

N. Ollivier et al.; Angew. Chem. Int. Ed. Engl. 2012; 51:209.

J. Dheur et al.; J. Org. Chem. 2011; 76: 3194.

J. Dheur et al.; Org. Lett. 2011; 13: 14560.

N. Ollivier et al.; Org. Lett. 2010; 12: 5238.

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