REM Resin

Chemical name: Acryloylmethyl polystyrene

  • Product code:SR-1036
  • Particle size :100-200 mesh
  • DVB crosslinking :1% DVB
  • Loading:0.8-1.3 mmol/g

Starting at $92.00

Grouped product items
Qty Packing unit Price SKU
5 g
$92.00
SR-1036.0005
25 g
$356.50
SR-1036.0025
100 g
$1,196.00
SR-1036.0100
description

Resin with immobilized acrylic acid serves as support for the solid phase synthesis of tertiary amines. Immobilization of a primary or secondary amine via Michael addition is followed by quaternization with the appropriate alkyl halide. beta-Elimination yields the tertiary amine.

references

R. Brown et al.; J. Am. Chem. Soc. 1997; 119: 3288.

J. Cattney et al.; Bioorg. Med. Chem. Lett. 1999; 9: 1323.

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