News

Visit this regularly updated section to check out the latest additions to our portfolio, as well as the latest developments at Iris Biotech.

1. News Building Blocks Product Focus

   31/10/2023

   Peptide Nucleic Acids as Stable DNA and RNA Analogs

   One molecule, two identities: PNAs are composed of nucleobases arranged on a peptidic backbone. Discover our PNA building blocks as ready-to-use bases suitable for SPPS.

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2. News Product of the month Amino Acids Building Blocks

   17/10/2023

   PotM: Next Generation Lysine Side Chain Protecting Groups

   Sick of Lysine side chain protecting groups jumping around, yielding scrambled peptides? Check our various options to fine-tune protecting group stability vs. cleavability to optimize your peptide yield.

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3. News Linkerology

   17/10/2023

   Linkerology® on Metal & Ore Surfaces

   A heart of gold! Metals and ores - see here how their surfaces can be equipped with bifunctional organic linker molecules and thus be turned into modifiable biocompatible materials.

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4. News Drug Delivery Product Focus

   03/10/2023

   Selective Lysine Labeling with Squaric Acid

   Keeping control! PEGylating reagents with a squaric acid ethyl ester react chemoselectively with side chain amino functions of surface-accessible Lysines in proteins. Other functionalities are not affected.

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5. News Amino Acids Building Blocks Custom Synthesis

   03/10/2023

   Process Development – From Discovery to Scale-up

   Ongoing research efforts lead to the discovery of innovative building blocks and new APIs. However, for industrial applications, upscaling is required. Herein, we share the process development for Fmoc-Cys(Msbh)-OH.

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6. News Dates & Exhibitions Workshop Series

   28/09/2023

   Workshop Bioorthogonal Chemistry in the Context of cell-free Protein Synthesis

   You missed our workshop featuring Dr. Stefan Kubick (B4Pharmatech, Berlin)? Any further questions? Please get in contact via info@iris-biotech.de

    

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7. News Product of the month Click Chemistry Linkerology

   19/09/2023

   PotM: Multiconjugates via Simultaneous Double-Click Reaction

   Discover our new building block 4-(azido-propyl-tetrazine)phenylalanine (pTAF) and make use of the orthogonality of the 2^nd and 3^rd generation Click reaction to build multiconjugates via double-Click.

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8. News Linkerology

   19/09/2023

   Conjugating Small Molecule Drugs

   You want to attach your small molecule to a certain carrier? Let’s analyze the functional groups present and discuss Linkerology® possibilities for permanent or trigger-inducible, tracelessly-cleavable linkage.

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9. News Click Chemistry Linkerology

   22/08/2023

   Cell-Free Bioengineering & Linkerology®

   Bioengineering in combination with Linkerology®. Check out the unique options for membrane proteins, recombinant immunotoxins (RITs) and novel antibody-drug conjugates.

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10. News Product of the month Reagents

    09/08/2023

    PotM: TCEP as Versatile Reducing Agent

    TCEP is an effective reductant for disulfide bonds and a versatile reagent for various applications in protein science with distinct advantages compared to DTT and BME.

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