Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Quick contact
Please send me more information about
Liraglutide Standard
Chemical name: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(gamma-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH // Synonyms: N26-(Hexadecanoyl-gamma-glutamyl)-(34-arginine)GLP-1-(7-37), Lys(gamma-Glu-palmitoyl)26,Arg34)-GLP-1 (7-37), ), One letter Code:HAEGTFTSDVSSYLEGQAAK(gamma-Glu-palmitoyl)EFIAWLVRGRG
- Product code:LS-4051
- CAS No.:204656-20-2
- Formula:C172H265N43O51
- Molecular weight:3751.26 g/mol
- Purity :min. 99.0%, no single impurity
Starting at Please inquire
description
20mg per vial net peptide content, as peptide standard for quantitative analysis. Glucagon-Like-Peptide-1 (GLP-1) agonist used for the treatment of type 2 diabetes. It is an incretin mimetic stimulating the release and synthesis of insulin into the blood by the intestine in response to food. It is only active in the presence of high circulating glucose levels. It also slows the passage of food through the gut and reduces appetite.
references
Innovative chemical synthesis and conformational hints on the lipopeptide liraglutide; I. Guryanov, A. Bondesan, D. Visentini, A. Orlandin, B. Biondi, C. Toniolo, F. Formaggio, A. Ricci, J. Zanon and W. Cabri; J Pept Sci 2016; 22: 471-9. https://doi.org/10.1002/psc.2890
Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide; J. Lau, P. Bloch, L. Schäffer, I. Pettersson, J. Spetzler, J. Kofoed, K. Madsen, L. B. Knudsen, J. McGuire, D. B. Steensgaard, H. M. Strauss, D. X. Gram, S. M. Knudsen, F. S. Nielsen, P. Thygesen, S. Reedtz-Runge and T. Kruse; Journal of medicinal chemistry 2015; 58: 7370-7380. https://doi.org/10.1021/acs.jmedchem.5b00726
The human GLP-1 analogs liraglutide and semaglutide: absence of histopathological effects on the pancreas in nonhuman primates; C. F. Gotfredsen, A. M. Molck, I. Thorup, N. C. Nyborg, Z. Salanti, L. B. Knudsen and M. O. Larsen; Diabetes 2014; 63: 2486-97. https://doi.org/10.2337/db13-1087
Differential chemistry (structure), mechanism of action, and pharmacology of GLP-1 receptor agonists and DPP-4 inhibitors; J. J. Neumiller; J Am Pharm Assoc (2003) 2009; 49 Suppl 1: S16-29. https://doi.org/10.1331/JAPhA.2009.09078
Liraglutide in type 2 diabetes: from pharmacological development to clinical practice; M. C. Rossi and A. Nicolucci; Acta Biomed 2009; 80: 93-101.
Potential of liraglutide in the treatment of patients with type 2 diabetes; C. F. Deacon; Vasc Health Risk Manag 2009; 5: 199-211. https://doi.org/10.2147/vhrm.s4039
Bulk or large quantity order?
Do you need larger quantities for your development or production?
Do you need further information about this product?
get in contact
Related Products
![Structure image for E[c(RGDfK)]c(RGDfK)](https://www.iris-biotech.de/media/catalog/product/L/S/LS-3980.svg?width=240&height=140&store=global&image-type=small_image)
![Structure image for ICG-E[c(RGDfK)]2](https://www.iris-biotech.de/media/catalog/product/L/S/LS-3950.svg?width=240&height=140&store=global&image-type=small_image)
![Structure image for cyclo-[RGDfK(TPP)]](https://www.iris-biotech.de/media/catalog/product/L/S/LS-3920.svg?width=240&height=140&store=global&image-type=small_image)
Related news
-
News Amino Acids Building Blocks Product FocusPeptide Blockbusters Liraglutide and Semaglutide
view details
We found other products you might like!
![Structure image for cyclo-[RGDfK(TPP)]](https://www.iris-biotech.de/media/catalog/product/L/S/LS-3920.svg?width=216&height=140&store=global&image-type=small_image)
